EDVOTEK Cancer Gene Detection Kit
EDVOTEK Cancer Gene Detection Kit
Product code: B8R06000
Product Description
*Please Note: This is a simulated Gene Detection kit which has been developed for use in education. It is not suitable for diagnostics or clinical use.*
Immortality through uncontrolled cell division is a characteristic of cancer cells. The p53 gene is a tumour suppressor gene which prevents this. Mutations in this gene are present in more than 50% of cancers. Testing people for mutations in their p53 gene can indicate an increased risk in developing cancer. These tests raise intriguing ethical questions for both the individual tested and the family of an individual who chooses to be tested.
In this experiment, students determine a pedigree for a family suspected to be carriers of mutations in their p53 genes. A DNA test indicates their likelihood of developing cancer.
This Cancer Gene Detection Kit includes the reagents needed to produce up to 8 electrophoresis gels.
- Group Size: For 8 gels
- Storage: Room Temperature stable, storage of Ready-to Load QuickStrip™ DNA samples in the refrigerator is recommended.
- Time Required: Complete in 45 minutes
The kit includes:
- Full instructions
- Ready-to Load QuickStrip™ DNA samples
- UltraSpec-Agarose™
- Electrophoresis Buffer (50x)
- Practice Gel Loading Solution
- FlashBlue™ DNA Stain
- InstaStain® Blue Cards
- Disposable pipettes
Additional required materials (not included with the kit):
- DNA Electrophoresis Tank, with accessories including casting trays, micropipettes & special power supply (B8R03273)
- Adjustable Micropipette (B8R05604)
- Micropipette Tips (PP00052738)
- Illuminator - optional (PP00052452)
- Microwave or hot plate (B8R04379)
- Discover the molecular biology behind familial cancers
- Explore how oncologists use pedigrees and molecular diagnostics
- Construct a family’s pedigree for Li-Fraumeni syndrome
- Perform agarose gel electrophoresis to separate different sized DNA molecules
- Load, run, analyze, and size control samples and a patient’s blood, tumor, and tissue samples to identify mutations in their p53 gene
- A-Level Genetics: Principles & Applications of Electrophoresis
- Cancer Gene Detection
- Full supporting materials included.
- EDVOTEK YouTube Channel is full of useful resources.
- When visualising completed gels using a white light box, cover the light box with clingfilm to prevent any damage.
Further Information
- Age Recommended from
- 16 Years
- Brand
- Edvotek
- Number of Lab Groups per Kit
- 8 electrophoresis gels / lab groups
- Product Type
- Electrophoresis Experiment Kit - Cancer Gene Detection
- Storage
- Ready-to Load QuickStrip™ DNA samples - Fridgeother reagents - Room Temperature
- Time Required
- Complete in 45 minutes
Documents
Useful Links
*Please Note: This is a simulated Gene Detection kit which has been developed for use in education. It is not suitable for diagnostics or clinical use.*
Immortality through uncontrolled cell division is a characteristic of cancer cells. The p53 gene is a tumour suppressor gene which prevents this. Mutations in this gene are present in more than 50% of cancers. Testing people for mutations in their p53 gene can indicate an increased risk in developing cancer. These tests raise intriguing ethical questions for both the individual tested and the family of an individual who chooses to be tested.
In this experiment, students determine a pedigree for a family suspected to be carriers of mutations in their p53 genes. A DNA test indicates their likelihood of developing cancer.
This Cancer Gene Detection Kit includes the reagents needed to produce up to 8 electrophoresis gels.
- Group Size: For 8 gels
- Storage: Room Temperature stable, storage of Ready-to Load QuickStrip™ DNA samples in the refrigerator is recommended.
- Time Required: Complete in 45 minutes
The kit includes:
- Full instructions
- Ready-to Load QuickStrip™ DNA samples
- UltraSpec-Agarose™
- Electrophoresis Buffer (50x)
- Practice Gel Loading Solution
- FlashBlue™ DNA Stain
- InstaStain® Blue Cards
- Disposable pipettes
Additional required materials (not included with the kit):
- DNA Electrophoresis Tank, with accessories including casting trays, micropipettes & special power supply (B8R03273)
- Adjustable Micropipette (B8R05604)
- Micropipette Tips (PP00052738)
- Illuminator - optional (PP00052452)
- Microwave or hot plate (B8R04379)
- Discover the molecular biology behind familial cancers
- Explore how oncologists use pedigrees and molecular diagnostics
- Construct a family’s pedigree for Li-Fraumeni syndrome
- Perform agarose gel electrophoresis to separate different sized DNA molecules
- Load, run, analyze, and size control samples and a patient’s blood, tumor, and tissue samples to identify mutations in their p53 gene
- A-Level Genetics: Principles & Applications of Electrophoresis
- Cancer Gene Detection
- Full supporting materials included.
- EDVOTEK YouTube Channel is full of useful resources.
- When visualising completed gels using a white light box, cover the light box with clingfilm to prevent any damage.
Further Information
- Age Recommended from
- 16 Years
- Brand
- Edvotek
- Number of Lab Groups per Kit
- 8 electrophoresis gels / lab groups
- Product Type
- Electrophoresis Experiment Kit - Cancer Gene Detection
- Storage
- Ready-to Load QuickStrip™ DNA samples - Fridgeother reagents - Room Temperature
- Time Required
- Complete in 45 minutes
